Wound Care Certified (WCC) Certification 2025 – 400 Free Practice Questions to Pass the Exam

The primary component of the skin's waterproof barrier is keratin. Keratin is a fibrous protein that forms a significant part of the upper layer of the skin, known as the stratum corneum. This layer consists of dead skin cells embedded in a lipid matrix that contributes to the skin's barrier function.

Keratin's unique structure provides strength and resilience, which helps prevent water loss from the body and protects the underlying layers of skin from external environmental factors, such as pathogens and pollutants. Its hydrophobic properties are essential for maintaining the skin's integrity and hydration levels.

While collagen is vital for the skin's structural support and elasticity, and elastin contributes to the skin's flexibility, they do not play a direct role in creating the waterproof barrier. Hyaluronic acid is important for moisture retention but is not a structural component in barrier formation. Thus, keratin is crucial for establishing and maintaining the skin's waterproof barrier.